In the early days of EPA testing, this presented a problem for Porsche. They were told that if they wanted to sell a car at a dealership whos altitude was 5,000 feet or above, they had to have the car certified not only in Ann Arbor Michigan but in Denver Colorado as well. This initially presented a problem which required a change of jets just prior to the car being transported to Colorado from Michigan.
This also presented a problem for me when I would drive these cars from Colorado back to Calif. Once I got to St. George Utah, I'd have to change jets in those triple Webers. The early mechanical injection required a lot of equipment to adjust the mixture so they said do nothing until I got back to California, the would then re-adjust the mixture and richen up the fuel delivery. Finally, in 1973, they switched to CIS injection and although it was fuel Injection, it was crude. I would have to richen up the mixture by placing a 3mm allen wrence into the fuel injection distributor and adjust the mixture by sound.
Later, when an 02 sensor was added no adjustments were needed.
I know a few people that live in Big Bear (Elevation 6,700 feet) They have hot rods and when they come down to the valley with these cars, Many of them just switch carburetors as it's much easier to change carb's than the jets