Hola JJ:
I grew up hearing that you always want to keep these engines rev'd at 3,000 or higher. The biggest reason was to keep the fan spinning fast enough to provide adequate cooling. That was the reason that Porsche went to the smaller diameter 356 fan pulley - to get the fan speed up when running the taller final drive ratio, and, hence, lower engine speed.
There's nothing wrong with having the engine spinning at 3,200 or so at 70 mph - that's even what the Berg 5-speed tranny's did, since they didn't have a big overdrive 4th. In fact, the Berg 5-speed had the same 4'th gear ratio as a stock VW - what they DID is provide close ratio gearing on 1 - 4 and then the usual .87 or so fourth.
OK, then...to answer your question, crank up your calculator and do the math on those fourth gear ratios and whatever you want as a rear-end gear-set, and see what the engine will be turning for RPM's at 70mph, given the size of the rear tire circumference and the differential gear ratio in fourth. If it's anywhere North of 3,000 RPM that's probably OK, but not over 3500. If you decide to run a 356 fan pulley regardless of the ratio set you choose, that's probably a good decision, too. I used to have something in Excel that did this sort of thing, but have just migrated over to a Mac (yay!) and can't find my old spreadsheet - it wasn't hard to construct, anyway...
I, personally, wouldn't run a so-called "Freeway flyer" with a higher geared rear end ratio with anything less than a 2,110, and, even then, I would have a 356 fan pulley and STILL would worry about keeping it cool. You might get 4 - 5 more miles per gallon, but can easily eat that savings up buying an external oil cooler to keep the oil cool(er), but the REAL benefit of the 356 pulley is increased air flow across the heads - where cooling is much more important.
Besides, I'm one of those guys who rarely get higher than third gear around town...
Gordon