Several things to consider. The first and foremost is how are you going to cool the engine??? More cubic centimeter displacement means more heat. More heat means less engine longevity. Auxillary oil coolers with fans "help" as does an increased oil supply (full flow system with externally mounted oil filter (1 quart) an external oil cooler working in conjunction with the dog house cooler is probably good for at least 1 quart of oil, a deep engine sump varies between 1.5 and 3 quarts. (depends on your ground clearance) The stock engine holds 3 quarts. As the oil cools, it aids in the transfer of heat away from the cylinders and helps to cool internal moving parts. Fresh air is blown across the cylinder and cylinde head cooling fins to keep them cool. (Thats the extent of your cooling system) I've seen where owners have done some ingenious metal fabrication to scoop up clean air from beneath their cars and direct it towards the fan intake with great success.
In my opinion, the 2110 is more durable than a 2332, especially since both will be contained within a hot engine compartment.
VW engine 101,, Most, if all VW big displacement engines start life as if they were a stock 1,600 cc VW.. The case and the heads have to be machined to accept larger parts. Stock engines had 85.5mm pistons and a 69mm crank shaft stroke.
The 2332 consist of 94mm pistons and a 84mm crank. The 2110 engine has 90.5 mm pistons and a 82mm crank. It's obvious to see that the cylinder heads, cylinder deck and internals will have to be machined more than the 2110 to accomodate the larger parts and rotaing mass.
As more material is removed, the case and heads become weaker and with less metal, comes less heat dissapation. Also as more torque/horsepower are produced, more heat is produced.
Constant cylinder head temperature and oil pressure/temperature monitoring is critical to a large displacement engine. Especially in a closed engine compartment.
Both engines will live for some time but you have to make up your mind based on facts rather than emotion.